HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: LHX8 (Q68G74)
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Gene: LHX8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 356
+	Hs
		1148497 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		LHX6_HUMAN (15-344): 3.69e-64: 209: 57.83
+	Hs
		238113 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		LMX1B_HUMAN (70-354): 1.67e-61: 203: 30.03
+	Hs
		899916 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		ISL1_HUMAN (62-336): 3.56e-58: 193: 30.10
+	Hs
		638491 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		RBTN1_HUMAN (75-194): 6.45e-54: 176: 39.02
+	Ce
		104771 LIN11_CAEEL (7-156): 1.29e-39: 139: 29.14		LIM7_CAEEL (26-284): 8.36e-50: 174: 28.44
+	Ce
		104772 HM14_CAEEL (1-157): 1.01e-39: 138: 28.30		LIM7_CAEEL (26-284): 8.36e-50: 174: 28.44
+	Ce
		447531 HM14_CAEEL (1-157): 1.01e-39: 138: 28.30		MEC3_CAEEL (50-282): 1.24e-49: 170: 24.18
+	Dm
		1368258 Q9VJ37_DROME (21-141): 2.89e-48: 165: 41.46		Q9VJ00_DROME (13-130): 8.73e-20: 92.3: 17.60
+	Dm
		114751 P92031_DROME (21-141): 3.63e-48: 164: 41.46		M9PD53_DROME (13-130): 6.36e-20: 92.6: 17.60
+	Dm
		112552 Q9VJ37_DROME (21-141): 2.89e-48: 165: 41.46		M9NCY1_DROME (13-130): 1.6e-19: 90.7: 17.60
+	Mm
		903797 LMO4_MOUSE (1-165): 1.95e-43: 143: 100.00		LMO4_MOUSE (75-186): 4.29e-25: 101: 44.35
+	Hs
		1148484 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		ISL2_HUMAN (8-131): 1.21e-16: 81.9: 12.21
+	Hs
		903763 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		LHX4_HUMAN (13-129): 1.04e-21: 96.9: 16.13
+	Hs
		899929 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LHX4_HUMAN (13-129): 1.04e-21: 96.9: 16.13
+	Hs
		899927 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LMX1A_HUMAN (15-130): 1.62e-21: 96.5: 16.39
+	Mm
		839895 ISL1_MOUSE (22-162): 3.73e-39: 137: 36.55		LHX3_MOUSE (3-129): 6.89e-20: 91.9: 15.79
+	Hs
		899935 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LHX3_HUMAN (3-129): 6.66e-20: 91.9: 17.16
+	Hs
		903764 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		ISL2_HUMAN (8-131): 1.21e-16: 81.9: 12.21
+	Ce
		590580 HM14_CAEEL (1-157): 1.01e-39: 138: 28.30		HM14_CAEEL (15-136): 2.61e-16: 81.1: 18.46
+	Hs
		899930 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		ISL2_HUMAN (8-131): 1.21e-16: 81.9: 12.21