HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: LDB1 (Q86U70)
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (hLdb1) (Nuclear LIM interactor)
Gene: LDB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 12727888, 25416956, 12925972, 32296183, 24981860, 15231748, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LID~LIM
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005667 - transcription regulator complex
GO:0030334 - regulation of cell migration
GO:0031252 - cell leading edge
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 165
Hs

1 411
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024