HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: LHX4 (Q969G2)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	24981860, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0008045 - motor neuron axon guidance GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 390
+	Hs
		899929 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LHX4_HUMAN (1-390): 1.1e-107: 323: 100.00
+	Hs
		1251418 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		LHX4_HUMAN (1-390): 1.1e-107: 323: 100.00
+	Hs
		899935 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LHX3_HUMAN (1-390): 1.94e-87: 271: 60.25
+	Mm
		839895 ISL1_MOUSE (22-162): 3.73e-39: 137: 36.55		LHX3_MOUSE (6-390): 7.2e-82: 257: 60.41
+	Dm
		114751 P92031_DROME (21-141): 3.63e-48: 164: 41.46		M9PD53_DROME (26-384): 1.23e-68: 227: 49.59
+	Dm
		1368258 Q9VJ37_DROME (21-141): 2.89e-48: 165: 41.46		Q9VJ00_DROME (26-384): 2.84e-68: 225: 49.59
+	Dm
		112552 Q9VJ37_DROME (21-141): 2.89e-48: 165: 41.46		M9NCY1_DROME (26-384): 5.18e-69: 224: 49.59
+	Hs
		899927 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		LMX1A_HUMAN (2-347): 2.28e-68: 222: 27.90
+	Hs
		238113 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		LMX1B_HUMAN (10-347): 2.11e-62: 207: 28.00
+	Hs
		1148484 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		ISL2_HUMAN (21-319): 1.05e-47: 167: 28.02
+	Hs
		1148497 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		LHX6_HUMAN (8-290): 1.23e-46: 165: 27.78
+	Hs
		899916 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		ISL1_HUMAN (20-321): 6.12e-51: 175: 27.57
+	Hs
		903764 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		ISL2_HUMAN (21-319): 1.05e-47: 167: 28.02
+	Hs
		899930 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		ISL2_HUMAN (21-319): 1.05e-47: 167: 28.02
+	Ce
		447531 HM14_CAEEL (1-157): 1.01e-39: 138: 28.30		MEC3_CAEEL (2-246): 3.67e-47: 165: 25.16
+	Hs
		903736 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31
+	Mm
		903797 LMO4_MOUSE (1-165): 1.95e-43: 143: 100.00		LMO4_MOUSE (29-150): 2.22e-31: 118: 43.31
+	Ce
		590580 HM14_CAEEL (1-157): 1.01e-39: 138: 28.30		HM14_CAEEL (88-390): 1.5e-13: 73.1: 10.79
+	Hs
		638491 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		RBTN1_HUMAN (89-189): 8.78e-11: 61.9: 16.83