HitPredict

Interactor 1: NTF2 (P61970)
Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15)
Gene: NUTF2

Interactor 2: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	32296183, 8707840, unassigned1304
Identification Methods	two hybrid, pull down, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017056 - structural constituent of nuclear pore GO:0031965 - nuclear membrane GO:0044613 - nuclear pore central transport channel GO:0051028 - mRNA transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 507
+	Hs
		1030323 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		NUP54_HUMAN (1-507): 1.14e-157: 459: 100.00
+	Hs
		727246 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		727332 G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		727234 NTF2_HUMAN (1-127): 3.29e-51: 160: 100.00		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		857971 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44
+	Hs
		867095 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		SC24C_HUMAN (8-332): 8.74e-10: 63.5: 9.76
+	Hs
		1293170 G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Hs
		727319 NXT2_HUMAN (6-123): 6.69e-39: 129: 24.22		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Dm
		1167369 Q6WAR0_DROME (91-125): 6.66e-10: 52.5: 40.00		NUP54_DROME (20-265): 7.39e-09: 60.4: 11.74