HitPredict

Interactor 1: NTF2 (P61970)
Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15)
Gene: NUTF2

Interactor 2: TNPO1 (Q92973)
Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)
Gene: TNPO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0031267 - small GTPase binding GO:0061608 - nuclear import signal receptor activity GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 898
+	Hs
		1030400 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		TNPO1_HUMAN (1-898): 0: 663: 100.00
+	Hs
		155567 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		TNPO2_HUMAN (11-898): 0: 613: 84.30
+	Hs
		1030246 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		IMB1_HUMAN (21-862): 1.01e-87: 300: 16.15
+	Hs
		874498 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		XPO2_HUMAN (14-897): 9.98e-87: 299: 12.98
+	Hs
		903812 NTF2_HUMAN (1-127): 3.29e-51: 160: 100.00		IMB1_HUMAN (21-862): 1.01e-87: 300: 16.15
+	Hs
		312257 G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96		IPO7_HUMAN (21-851): 6.08e-77: 273: 14.49
+	Dm
		185894 NXT1_DROME (9-123): 9.5e-35: 118: 27.27		IMB_DROME (15-862): 3.26e-83: 288: 17.78