HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: ITK (Q08881)
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)
Gene: ITK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8810341
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007165 - signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 620
+	Mm
		904243 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ITK_MOUSE (1-620): 0: 764: 93.29
+	Hs
		522880 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		SRC_HUMAN (95-618): 0: 541: 31.35
+	Hs
		442807 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HCK_HUMAN (122-618): 0: 523: 33.86
+	Hs
		412116 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		FYN_HUMAN (158-618): 9.21e-180: 521: 35.48
+	Mm
		639439 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		LYN_MOUSE (147-618): 1.39e-168: 492: 36.67
+	Hs
		433678 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		LYN_HUMAN (144-618): 5.71e-167: 487: 35.19
+	Hs
		782763 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CSK_HUMAN (167-620): 1.48e-148: 438: 34.63
+	Hs
		522876 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		SRC_HUMAN (95-618): 0: 541: 31.35
+	Hs
		522998 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRC_HUMAN (95-618): 0: 541: 31.35
+	Hs
		789115 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		FRK_HUMAN (144-619): 1.28e-168: 492: 33.27
+	Hs
		434107 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		LYN_HUMAN (144-618): 5.71e-167: 487: 35.19
+	Hs
		433946 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		LYN_HUMAN (144-618): 5.71e-167: 487: 35.19