HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	26318153, 37071682, 22365833, 26496610, 35271311
Identification Methods	affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006396 - RNA processing GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 355
+	Mm
		904259 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		HNRPD_MOUSE (1-355): 8.17e-72: 229: 95.49
+	Hs
		162001 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Mm
		904318 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ROAA_MOUSE (29-305): 5.29e-52: 175: 50.71
+	Mm
		904286 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ROA3_MOUSE (64-265): 2.72e-50: 174: 37.02
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (88-272): 2.51e-42: 157: 16.93
+	Mm
		291908 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ROA2_MOUSE (98-277): 8.38e-39: 142: 41.40
+	Hs
		609791 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		453252 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Mm
		825776 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ROA1_MOUSE (63-177): 2.53e-19: 89.3: 26.83
+	Mm
		1112164 FUBP2_MOUSE (200-463): 1.63e-12: 71.6: 14.29		HNRPD_MOUSE (1-355): 8.17e-72: 229: 95.49
+	Hs
		1048165 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1016054 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		Q12771_HUMAN (1-292): 6.63e-61: 198: 80.48
+	Dm
		112939 M9NF14_DROME (115-458): 5.28e-26: 113: 17.77		SQD_DROME (78-264): 4.23e-42: 151: 42.55
+	Dm
		995764 Q7KHL0_DROME (365-458): 2.63e-18: 89.3: 55.32		SQD_DROME (78-264): 4.23e-42: 151: 42.55
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		453375 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		453516 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Mm
		825779 FUBP2_MOUSE (200-463): 1.63e-12: 71.6: 14.29		ROA1_MOUSE (63-177): 2.53e-19: 89.3: 26.83
+	Hs
		963557 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50