HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: KHDR2 (Q5VWX1)
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1)
Gene: KHDRBS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.920

Property	Details
Experiments	16189514, 32296183, 17643375, unassigned1654, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	KH_1~KH_1, KH_1~Qua1
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 349
+	Hs
		267489 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		KHDR3_HUMAN (3-349): 2e-141: 406: 64.87
+	Mm
		904260 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		KHDR1_MOUSE (3-349): 9.08e-129: 377: 62.32
+	Hs
		903898 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		904090 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		903954 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Hs
		1139265 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		KHDR2_HUMAN (1-349): 6.2e-151: 430: 100.00
+	Hs
		128202 IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57		KHDR2_HUMAN (1-349): 6.2e-151: 430: 100.00
+	Hs
		991773 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		991841 FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64		KHDR1_HUMAN (3-349): 4.21e-120: 355: 62.50
+	Hs
		884395 PCBP4_HUMAN (380-457): 8.52e-20: 93.1: 38.46		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		1072161 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		884346 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		1071974 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		1294228 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Hs
		1299697 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		QKI_HUMAN (5-272): 2.33e-89: 273: 33.80
+	Ce
		107490 HRPK1_CAEEL (110-220): 1.55e-10: 64.7: 18.02		ASD2_CAEEL (4-189): 1.48e-71: 231: 38.54
+	Hs
		1071877 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01
+	Hs
		1075724 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		SF01_HUMAN (8-209): 6.71e-57: 196: 27.01