HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002102 - podosome GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0042995 - cell projection GO:0045296 - cadherin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 368
+	Hs
		904116 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		903873 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Mm
		904258 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38
+	Rn
		904380 HNRPK_RAT (1-463): 1.31e-129: 385: 100.00		GRB2_RAT (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		1052204 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		924755 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924788 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924908 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38