HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: DDX56 (Q9NY93)
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)
Gene: DDX56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 547
+	Hs
		904065 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		DDX17_HUMAN (4-467): 9.05e-132: 402: 23.44
+	Mm
		904255 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		DDX17_MOUSE (4-472): 5.22e-132: 400: 23.19
+	Hs
		571383 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Rn
		904402 HNRPK_RAT (1-463): 1.31e-129: 385: 100.00		Q6AYI1_RAT (4-418): 2.13e-129: 392: 24.52
+	Mm
		904317 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		DDX27_MOUSE (2-424): 2.27e-49: 183: 30.84
+	Hs
		757533 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		IF4A3_HUMAN (9-403): 3.82e-44: 163: 28.12
+	Mm
		904310 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		IF4A3_MOUSE (9-403): 6.28e-44: 162: 27.87
+	Hs
		571464 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		571615 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		DDX5_HUMAN (4-418): 1.65e-129: 393: 24.52
+	Hs
		134054 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		134268 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		134166 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Hs
		181700 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DDX3Y_HUMAN (6-447): 6.08e-120: 369: 23.85
+	Hs
		134229 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Dm
		112657 M9NDY6_DROME (26-463): 5.26e-71: 235: 21.32		DDX6_DROME (3-407): 2.68e-45: 167: 29.80
+	Dm
		112937 M9NF14_DROME (115-458): 5.28e-26: 113: 17.77		DDX6_DROME (3-407): 2.68e-45: 167: 29.80
+	Dm
		90552 E1JGN7_DROME (365-459): 2.68e-18: 89.3: 53.68		DDX6_DROME (3-407): 2.68e-45: 167: 29.80
+	Hs
		640486 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DDX6_HUMAN (9-407): 9.42e-46: 169: 29.78
+	Hs
		640683 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		DDX6_HUMAN (9-407): 9.42e-46: 169: 29.78
+	Hs
		640585 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		DDX6_HUMAN (9-407): 9.42e-46: 169: 29.78