HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	26816005
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 424
+	Mm
		904305 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33
+	Hs
		88029 D3DTW3_HUMAN (38-232): 6.83e-23: 102: 18.09		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1072199 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1072053 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1121936 Q53SS8_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1349154 IF2B1_HUMAN (175-462): 1.88e-09: 62: 11.57		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		128327 IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1072115 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Hs
		1121935 Q53SS8_HUMAN (23-127): 3.42e-12: 69.7: 23.15		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Mm
		888826 PCBP1_MOUSE (23-127): 3.42e-12: 69.7: 23.15		Q8VD35_MOUSE (13-95): 4.78e-11: 65: 31.33