HitPredict

Interactor 1: HNRPK (P61979)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Gene: Hnrnpk

Interactor 2: SRS10 (Q9R0U0)
Serine/arginine-rich splicing factor 10 (FUS-interacting serine-arginine-rich protein 1) (Neural-salient serine/arginine-rich protein) (Neural-specific SR protein) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: Srsf10

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26336360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0043679 - axon terminus GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Mm			1 262
+	Hs
		904192 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46
+	Hs
		903884 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Mm
		904238 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79
+	Mm
		904266 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRSF2_MOUSE (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35
+	Hs
		266997 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		1072063 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46
+	Hs
		884293 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		951975 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Mm
		888801 PCBP1_MOUSE (23-127): 3.42e-12: 69.7: 23.15		SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79
+	Hs
		951974 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		952198 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		1031509 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		516530 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		516769 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		516642 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		963557 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91
+	Hs
		963587 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91