HitPredict

Interactor 1: HNRPK (P61980)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (dC stretch-binding protein) (CSBP)
Gene: Hnrnpk

Interactor 2: GRB2 (P62994)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	16518874
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Rn			1 217
+	Mm
		904258 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		GRB2_MOUSE (1-217): 2.48e-76: 230: 99.54
+	Hs
		903873 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		782763 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CSK_HUMAN (2-139): 3.92e-24: 100: 36.24
+	Hs
		904174 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67
+	Hs
		548674 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Mm
		654976 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		VAV_MOUSE (2-60): 8.53e-15: 74.6: 42.37
+	Hs
		412116 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		442807 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39
+	Hs
		903956 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00
+	Hs
		433678 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Mm
		639439 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		LYN_MOUSE (129-215): 2.66e-11: 64.2: 22.47
+	Hs
		522880 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		275183 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		GRAP2_HUMAN (3-55): 1.58e-10: 61.3: 39.62
+	Hs
		924755 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924788 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		434107 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		522876 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		522998 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		433946 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		789115 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		FRK_HUMAN (150-212): 6.98e-11: 62.7: 27.78