HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29669786, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome GO:0098793 - presynapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 330
+	Hs
		905812 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Mm
		906225 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Mm
		905328 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		905846 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Sp
		532282 RAD24_SCHPO (3-247): 8.91e-135: 381: 60.82		PP11_SCHPO (6-329): 0: 557: 82.41
+	Mm
		906229 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		PP1A_MOUSE (1-330): 0: 614: 99.70
+	At
		788328 14331_ARATH (4-244): 4.02e-141: 397: 59.67		PP15_ARATH (2-306): 0: 525: 76.47
+	Mm
		906231 1433T_MOUSE (2-245): 3e-105: 306: 70.73		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Sp
		621137 RAD24_SCHPO (3-247): 8.91e-135: 381: 60.82		PP12_SCHPO (8-303): 0: 538: 79.73
+	Hs
		683174 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Mm
		926530 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		PP1G_MOUSE (1-330): 0: 579: 90.66
+	Bt
		898865 1433Z_BOVIN (2-245): 2.39e-108: 314: 74.59		PP1G_BOVIN (1-330): 0: 579: 90.66
+	Hs
		909432 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30
+	Hs
		646689 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Zm
		36330 B6U284_MAIZE (2-247): 2.84e-141: 397: 59.68		A0A1D6LZA4_MAIZE (1-300): 5.89e-149: 422: 65.00
+	Mm
		915319 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		PP2AB_MOUSE (8-302): 1.41e-176: 492: 47.97