Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 33961781, 35271311, 36931259, 20936779, 31980649, 34349018, 35235311, 17979178, 21988832, 17085597, unassigned2173, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, cross-linking study, mass spectrometry studies of complexes, anti tag coimmunoprecipitation, two hybrid pooling approach, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0006605 - protein targeting
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 247
Hs

1 255
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Last updated: 15 Jul 2024