HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: CDK17 (Q00537)
Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)
Gene: CDK17

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	33961781, 35271311, 36931259, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 523
+	Hs
		909449 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK17_HUMAN (1-523): 0: 544: 100.00
+	Hs
		960433 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK17_HUMAN (1-523): 0: 544: 100.00
+	Hs
		909448 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625306 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		904446 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625296 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		960357 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625383 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		909447 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98
+	Hs
		909472 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	Hs
		904478 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	Hs
		960082 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98
+	Hs
		981945 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	At
		965298 14332_ARATH (4-244): 1.39e-141: 398: 61.32		MPK7_ARATH (161-519): 2.65e-138: 405: 30.06
+	Dm
		955007 1433E_DROME (1-243): 1.58e-140: 396: 63.37		Q7KM03_DROME (108-506): 5.01e-134: 400: 50.97
+	Dm
		955011 1433E_DROME (1-243): 1.58e-140: 396: 63.37		Q94888_DROME (87-506): 2.71e-134: 400: 48.50
+	Hs
		300632 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300631 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300636 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300628 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89