HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.949

The method score is based on:

Property Details
Experiments 26496610, 35271311, 36931259, 33961781, 17979178, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0005159 - insulin-like growth factor receptor binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0019904 - protein domain specific binding
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 247
Hs

1 246
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024