HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	33961781, 35271311, 36931259, 15324660, 36950384, 17353931, 28514442
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 763
+	Hs
		909539 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Mm
		910255 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DYR1A_MOUSE (1-763): 0: 610: 99.21
+	Hs
		910197 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DYR1B_HUMAN (57-600): 2.33e-137: 421: 68.13
+	Hs
		647862 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72
+	Mm
		910231 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		MARK3_MOUSE (105-758): 2.37e-123: 388: 17.87
+	Hs
		647860 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MARK3_HUMAN (105-758): 1.17e-123: 389: 17.72
+	Xl
		223344 O57468_XENLA (1-244): 4.25e-141: 397: 63.12		Q804T2_XENLA (105-761): 1.81e-121: 383: 17.49
+	Mm
		905331 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		MARK3_MOUSE (105-758): 2.37e-123: 388: 17.87
+	Hs
		909877 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53
+	Mm
		935481 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		MARK3_MOUSE (105-758): 2.37e-123: 388: 17.87
+	Hs
		910066 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DYRK4_HUMAN (132-590): 2.67e-118: 367: 35.78
+	Hv
		664586 1433A_HORVU (4-244): 1.28e-138: 391: 59.67		Q70YJ0_HORVU (70-673): 3.57e-119: 372: 21.04
+	Hs
		681770 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AKT1_HUMAN (38-466): 4.44e-117: 363: 19.42
+	Hs
		625306 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Hs
		909447 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12
+	Hs
		681766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AKT1_HUMAN (38-466): 4.44e-117: 363: 19.42
+	Hs
		625296 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Hs
		909828 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		HIPK4_HUMAN (157-478): 1.65e-53: 197: 38.30
+	At
		847169 14332_ARATH (4-244): 1.39e-141: 398: 61.32		AFC1_ARATH (141-485): 6.57e-53: 192: 32.17
+	Zm
		27099 B6SRI4_MAIZE (2-245): 2.63e-140: 395: 60.16		A0A1D6JDK3_MAIZE (136-478): 9.83e-51: 193: 33.58