HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: GAPD1 (Q14C86)
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6)
Gene: GAPVD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1478
+	Hs
		909576 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GAPD1_HUMAN (1-1478): 0: 2079: 100.00
+	Hs
		909664 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DAB2P_HUMAN (62-602): 5.14e-111: 382: 16.72
+	Hs
		904695 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DAB2P_HUMAN (62-602): 5.14e-111: 382: 16.72
+	Hs
		910133 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		NGAP_HUMAN (69-628): 8.13e-78: 283: 14.24
+	Hs
		905231 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		NGAP_HUMAN (69-628): 8.13e-78: 283: 14.24
+	Hs
		909931 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SYGP1_HUMAN (72-507): 6.42e-73: 270: 15.00
+	Mm
		99940 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		905008 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SYGP1_HUMAN (72-507): 6.42e-73: 270: 15.00
+	Mm
		99939 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		909774 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RASL3_HUMAN (94-635): 9.53e-71: 260: 16.72
+	Mm
		99953 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		SYGP1_MOUSE (72-447): 6.74e-73: 270: 15.26
+	Hs
		905227 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RABX5_HUMAN (1221-1477): 1.03e-67: 239: 20.83
+	Hs
		108670 G9K388_HUMAN (4-241): 9.01e-156: 439: 64.29		RIN3_HUMAN (1208-1475): 5.18e-48: 189: 17.69
+	Hs
		598455 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		NF1_HUMAN (144-468): 2.57e-58: 225: 18.26
+	Mm
		910233 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		NF1_MOUSE (144-468): 2.05e-57: 222: 17.98
+	Hs
		598454 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		NF1_HUMAN (144-468): 2.57e-58: 225: 18.26
+	Rn
		935722 1433F_RAT (1-246): 1.51e-136: 385: 86.99		NF1_RAT (144-468): 1.33e-59: 229: 18.29
+	Hs
		909924 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANR27_HUMAN (1214-1472): 7.13e-56: 214: 20.15
+	Hs
		72095 B3KNB4_HUMAN (1-247): 3.71e-138: 389: 99.60		RIN3_HUMAN (1208-1475): 5.18e-48: 189: 17.69
+	Mm
		910298 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		VP9D1_MOUSE (1221-1475): 5.12e-44: 173: 15.94