HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PDZ11 (Q5EBL8)
PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)
Gene: PDZD11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 140
+	Hs
		909633 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PDZ11_HUMAN (1-140): 6.57e-49: 155: 100.00
+	Hs
		982083 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		PDZ11_HUMAN (1-140): 6.57e-49: 155: 100.00
+	Mm
		57251 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		A2AKD7_MOUSE (5-137): 7.6e-29: 111: 25.93
+	Hs
		909851 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RPGF6_HUMAN (46-125): 1.54e-27: 108: 37.04
+	Mm
		57250 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		A2AKD7_MOUSE (5-137): 7.6e-29: 111: 25.93
+	Hs
		910200 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RPGF2_HUMAN (14-125): 2.92e-26: 104: 35.65
+	Hs
		904905 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RPGF6_HUMAN (46-125): 1.54e-27: 108: 37.04
+	Hs
		905302 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RPGF2_HUMAN (14-125): 2.92e-26: 104: 35.65
+	Hs
		982316 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		RPGF6_HUMAN (46-125): 1.54e-27: 108: 37.04
+	Hs
		982658 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		RPGF2_HUMAN (14-125): 2.92e-26: 104: 35.65
+	Mm
		910260 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DLG4_MOUSE (38-130): 2.79e-17: 78.8: 33.33
+	Mm
		905344 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		DLG4_MOUSE (38-130): 2.79e-17: 78.8: 33.33
+	Dm
		677686 1433E_DROME (1-243): 1.58e-140: 396: 63.37		DLG1_DROME (27-130): 2.29e-10: 59.2: 27.03
+	Mm
		57253 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		A2AKD7_MOUSE (5-137): 7.6e-29: 111: 25.93
+	Hs
		683569 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		RPGF6_HUMAN (46-125): 1.54e-27: 108: 37.04
+	Hs
		683851 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		RPGF2_HUMAN (14-125): 2.92e-26: 104: 35.65
+	Mm
		926845 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		RPGF2_MOUSE (14-125): 3.35e-25: 101: 35.65
+	Mm
		1143489 1433B_MOUSE (2-247): 8.57e-109: 315: 75.81		DLG4_MOUSE (38-130): 2.79e-17: 78.8: 33.33
+	Mm
		926805 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		DLG4_MOUSE (38-130): 2.79e-17: 78.8: 33.33
+	Dm
		664599 1433Z_DROME (2-242): 1.36e-108: 314: 74.69		DLG1_DROME (27-130): 2.29e-10: 59.2: 27.03