HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1121
+	Hs
		909680 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		910040 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		876345 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		876343 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125318 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Mm
		910223 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		CYH2_MOUSE (105-300): 1.44e-44: 168: 21.50
+	Hs
		904592 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CYH1_HUMAN (105-281): 4.55e-43: 164: 21.69
+	Hs
		910027 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		905112 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Mm
		93264 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		E9PXB7_MOUSE (59-486): 2.89e-28: 125: 13.02
+	Mm
		910302 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		NED4L_MOUSE (59-486): 8.19e-27: 120: 12.02
+	Mm
		93263 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		E9PXB7_MOUSE (59-486): 2.89e-28: 125: 13.02
+	Hs
		909930 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		905007 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Rn
		910358 1433E_RAT (1-244): 2.02e-141: 398: 63.53		NEDD4_RAT (11-97): 3.59e-19: 95.8: 25.93
+	Rn
		905367 1433G_RAT (1-247): 3.15e-139: 392: 100.00		NEDD4_RAT (11-97): 3.59e-19: 95.8: 25.93
+	Hs
		808077 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Hs
		904987 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		808076 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Mm
		808343 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64