HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: MAST2 (Q6P0Q8)
Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)
Gene: MAST2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1798
+	Hs
		909684 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST2_HUMAN (1-1798): 0: 1268: 100.00
+	Hs
		910182 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST1_HUMAN (160-1694): 0: 910: 60.19
+	Hs
		230856 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST3_HUMAN (148-1463): 0: 765: 59.16
+	Hs
		230855 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MAST3_HUMAN (148-1463): 0: 765: 59.16
+	Hs
		909585 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KPCD1_HUMAN (68-854): 1.37e-155: 503: 17.68
+	Hs
		910187 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SIK3_HUMAN (493-1627): 1.61e-149: 498: 16.05
+	Hs
		904582 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCD1_HUMAN (68-854): 1.37e-155: 503: 17.68
+	Hs
		905284 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SIK3_HUMAN (493-1627): 1.61e-149: 498: 16.05
+	Hs
		909795 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ULK2_HUMAN (512-1407): 1.01e-147: 485: 20.17
+	Zm
		45993 B6SRI4_MAIZE (2-245): 2.63e-140: 395: 60.16		A0A1Q0ZG94_MAIZE (142-876): 6.73e-146: 486: 27.39
+	Hs
		681770 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AKT1_HUMAN (361-846): 3.61e-153: 480: 28.60
+	Hs
		566346 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCA_HUMAN (205-849): 2.73e-151: 483: 22.73
+	Hs
		681766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AKT1_HUMAN (361-846): 3.61e-153: 480: 28.60
+	Hs
		408587 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCB_HUMAN (205-849): 8.64e-148: 473: 22.12
+	At
		788319 14331_ARATH (4-244): 4.02e-141: 397: 59.67		KPK1_ARATH (442-859): 1.08e-140: 446: 30.25
+	Hs
		568616 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KAPCA_HUMAN (502-842): 4.8e-134: 423: 35.36
+	Hs
		910180 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ST38L_HUMAN (510-818): 6.95e-63: 224: 37.46
+	Hs
		164690 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST4_HUMAN (835-1710): 6.41e-17: 89.8: 13.21
+	Hs
		164689 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MAST4_HUMAN (835-1710): 6.41e-17: 89.8: 13.21
+	Hs
		164692 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MAST4_HUMAN (835-1710): 6.41e-17: 89.8: 13.21