HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	33961781, 35271311, 36931259, 37120454, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 1708
+	Hs
		909697 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		982159 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		683461 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		927182 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		647014 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		684134 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Dm
		955044 1433E_DROME (1-243): 1.58e-140: 396: 63.37		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62
+	Dm
		664664 1433Z_DROME (2-242): 1.36e-108: 314: 74.69		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62