HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 888
+	Hs
		909744 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH3R1_HUMAN (1-888): 1.17e-136: 431: 100.00
+	Hs
		909712 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		OTOG_HUMAN (355-783): 3.08e-49: 192: 17.27
+	Hs
		904746 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		OTOG_HUMAN (355-783): 3.08e-49: 192: 17.27
+	Mm
		910242 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SRBS2_MOUSE (428-502): 1.42e-22: 106: 44.32
+	Hs
		298967 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		299007 V9HW98_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		298965 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		277043 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		909551 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ARHG7_HUMAN (725-888): 1.36e-14: 80.3: 19.88
+	Hs
		909979 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		905042 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SH3G1_HUMAN (234-509): 1.3e-15: 81.4: 12.68
+	Hs
		909634 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		904551 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARHG7_HUMAN (725-888): 1.36e-14: 80.3: 19.88
+	Hs
		905065 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		275184 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GRAP2_HUMAN (835-887): 3.61e-12: 70.6: 28.30
+	Hs
		904655 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		909706 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DNMBP_HUMAN (4-190): 5.38e-11: 68.9: 15.10
+	Hs
		909849 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71
+	Hs
		904742 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DNMBP_HUMAN (4-190): 5.38e-11: 68.9: 15.10
+	Hs
		904904 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71