HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: RHG07 (Q96QB1)
Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12)
Gene: DLC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1528
+	Hs
		70666 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYO9A_HUMAN (146-1340): 3.77e-127: 442: 13.90
+	Hs
		70665 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYO9A_HUMAN (146-1340): 3.77e-127: 442: 13.90
+	Hs
		70671 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MYO9A_HUMAN (146-1340): 3.77e-127: 442: 13.90
+	Hs
		909659 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SYDE2_HUMAN (280-1349): 9.57e-119: 404: 13.54
+	Hs
		904691 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SYDE2_HUMAN (280-1349): 9.57e-119: 404: 13.54
+	Hs
		909650 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RHG21_HUMAN (295-1410): 2.55e-89: 324: 13.61
+	Hs
		904676 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG21_HUMAN (295-1410): 2.55e-89: 324: 13.61
+	Hs
		909873 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		HMHA1_HUMAN (335-1395): 1.35e-80: 292: 13.28
+	Hs
		909743 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRGP1_HUMAN (899-1344): 5.16e-79: 286: 15.45
+	Mm
		910285 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SRGP3_MOUSE (899-1347): 4.15e-77: 281: 15.97
+	Hs
		904781 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRGP1_HUMAN (899-1344): 5.16e-79: 286: 15.45
+	Hs
		905201 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG23_HUMAN (322-1358): 2.49e-77: 285: 12.64
+	Hs
		904704 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG17_HUMAN (831-1391): 1.77e-74: 269: 15.70
+	Hs
		904647 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG29_HUMAN (537-1350): 1.48e-72: 268: 11.98
+	Mm
		910284 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		RHG33_MOUSE (995-1363): 4.11e-70: 261: 19.22
+	Mm
		935571 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		RHG18_MOUSE (748-1418): 2.86e-76: 269: 15.43
+	Hs
		302638 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		FA13A_HUMAN (1039-1409): 6.7e-69: 255: 21.57
+	Hs
		302637 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		FA13A_HUMAN (1039-1409): 6.7e-69: 255: 21.57
+	Hs
		506563 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		BCR_HUMAN (1046-1273): 1.17e-56: 218: 23.93
+	Hs
		506562 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		BCR_HUMAN (1046-1273): 1.17e-56: 218: 23.93