HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SH23A (Q9BRG2)
SH2 domain-containing protein 3A (Novel SH2-containing protein 1)
Gene: SH2D3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 576
+	Hs
		909966 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH23A_HUMAN (1-576): 0: 633: 100.00
+	Hs
		904855 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SH2D3_HUMAN (9-574): 0: 602: 33.13
+	Hs
		411661 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		LCK_HUMAN (3-256): 1.89e-59: 207: 14.23
+	Hs
		789053 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ABL2_HUMAN (3-256): 1.71e-52: 195: 17.18
+	Hs
		337416 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ABL1_HUMAN (3-256): 8.1e-51: 190: 16.79
+	Hs
		789052 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ABL2_HUMAN (3-256): 1.71e-52: 195: 17.18
+	Hs
		337415 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ABL1_HUMAN (3-256): 8.1e-51: 190: 16.79
+	Hs
		850732 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		BMX_HUMAN (9-228): 2.68e-48: 180: 16.09
+	Hs
		789060 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		ABL2_HUMAN (3-256): 1.71e-52: 195: 17.18
+	Mm
		910263 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		CRK_MOUSE (3-246): 4.91e-51: 179: 21.17
+	Hs
		337436 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		ABL1_HUMAN (3-256): 8.1e-51: 190: 16.79
+	Hs
		802550 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CRK_HUMAN (3-246): 6.1e-51: 179: 21.17
+	Mm
		905345 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		CRK_MOUSE (3-246): 4.91e-51: 179: 21.17
+	Mm
		935515 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		CRK_MOUSE (3-246): 4.91e-51: 179: 21.17
+	Hs
		909427 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GRB2_HUMAN (3-166): 7.35e-45: 159: 19.21
+	Hs
		904426 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		GRB2_HUMAN (3-166): 7.35e-45: 159: 19.21
+	Dm
		954994 1433E_DROME (1-243): 1.58e-140: 396: 63.37		GRAP_DROME (3-164): 1.35e-40: 148: 21.05
+	Hs
		275184 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		GRAP2_HUMAN (3-149): 8.33e-34: 132: 29.94
+	Hs
		666056 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SHC1_HUMAN (1-117): 5.09e-32: 132: 32.26
+	Hs
		666055 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SHC1_HUMAN (1-117): 5.09e-32: 132: 32.26