HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 693
+	Hs
		910093 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		982553 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		909812 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		904853 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		982273 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		909755 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		904795 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		982221 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		297821 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		K0754_HUMAN (24-414): 1.17e-27: 122: 10.30
+	Hs
		909712 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		904746 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		904466 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		982175 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		979875 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		257595 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		257593 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		203217 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55
+	Hs
		257604 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		203222 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55
+	Hs
		257572 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54