HitPredict

Interactor 1: 1433G (P61982)
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: Ywhag

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	28671696, 19022416
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045202 - synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 247 Mm			1 724
+	Mm
		910260 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		1143489 1433B_MOUSE (2-247): 8.57e-109: 315: 75.81		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		926805 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Dm
		677686 1433E_DROME (1-243): 1.58e-140: 396: 63.37		DLG1_DROME (22-322): 5.59e-26: 116: 20.79
+	Hs
		904552 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		159186 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Hs
		982003 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		909845 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		904899 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		982311 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Dm
		664599 1433Z_DROME (2-242): 1.36e-108: 314: 74.69		DLG1_DROME (22-322): 5.59e-26: 116: 20.79
+	Hs
		683339 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		927034 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		646881 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		683563 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		927332 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55
+	Hs
		684030 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		647130 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55