HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26496610, 27173435, 26186194, 28514442, 29669786, 33961781, 34349018, 36652389
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos, Metallophos~STPPase_N, STPPase_N~STPPase_N
Common GO terms GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
and 13 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 330
Hs

1 327
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024