HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 793
+	Hs
		737759 PP1G_HUMAN (1-330): 0: 579: 90.66		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Mm
		906240 PP1A_MOUSE (1-330): 0: 614: 99.70		MYH6_MOUSE (1-792): 7.67e-30: 129: 10.87
+	Hs
		906052 PP1A_HUMAN (1-330): 0: 614: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		906423 PP1B_HUMAN (1-330): 0: 568: 87.88		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		724746 PP1A_HUMAN (1-330): 0: 614: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148613 PP1A_HUMAN (1-330): 0: 614: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		906549 PP1B_HUMAN (1-330): 0: 568: 87.88		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		724689 PP1G_HUMAN (1-330): 0: 579: 90.66		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		738090 PP1G_HUMAN (1-330): 0: 579: 90.66		ITSN2_HUMAN (3-406): 4.87e-21: 101: 16.75
+	Hs
		906645 PP1B_HUMAN (1-330): 0: 568: 87.88		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		906154 PP1A_HUMAN (1-330): 0: 614: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		905940 PP1A_HUMAN (1-330): 0: 614: 100.00		HYDIN_HUMAN (1-286): 7.73e-09: 61.7: 11.57
+	Hs
		724747 PP1B_HUMAN (1-330): 0: 568: 87.88		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		737818 PP1G_HUMAN (1-330): 0: 579: 90.66		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148470 PP1G_HUMAN (1-330): 0: 579: 90.66		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		906466 PP1B_HUMAN (1-330): 0: 568: 87.88		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148614 PP1B_HUMAN (1-330): 0: 568: 87.88		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		738064 PP1G_HUMAN (1-330): 0: 579: 90.66		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		906607 PP1B_HUMAN (1-330): 0: 568: 87.88		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Dm
		819254 PP1B_DROME (6-326): 0: 551: 83.49		Q0KI67_DROME (36-649): 2.65e-11: 69.6: 15.94