HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29669786, 25593058
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 644
+	Hs
		737785 PP1G_HUMAN (1-330): 0: 579: 90.66		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516441 PP1A_HUMAN (1-330): 0: 614: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516386 PP1G_HUMAN (1-330): 0: 579: 90.66		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516454 PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Sp
		532280 PP11_SCHPO (6-329): 0: 557: 82.41		PABP_SCHPO (2-414): 5.25e-64: 225: 25.12
+	Zm
		6224 B4FJL0_MAIZE (4-324): 0: 549: 73.21		A0A1D6E6L1_MAIZE (2-456): 6.76e-67: 232: 24.68
+	Hs
		582179 PP1A_HUMAN (1-330): 0: 614: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		582100 PP1G_HUMAN (1-330): 0: 579: 90.66		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		582180 PP1B_HUMAN (1-330): 0: 568: 87.88		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Mm
		857299 PP1B_MOUSE (1-330): 0: 568: 87.88		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12