Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: CDCA2 (Q69YH5)
Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man)
Gene: CDCA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 29764992
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~PP1_bind, PP1_bind~STPPase_N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0051301 - cell division
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 330
Hs

1 1023
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024