HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.615

Property	Details
Experiments	25852190, 28065597, 22321011
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, ubiquitin reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 1374
+	Hs
		737881 PP1G_HUMAN (1-330): 0: 579: 90.66		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		906508 PP1B_HUMAN (1-330): 0: 568: 87.88		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		906008 PP1A_HUMAN (1-330): 0: 614: 100.00		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		737908 PP1G_HUMAN (1-330): 0: 579: 90.66		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		906524 PP1B_HUMAN (1-330): 0: 568: 87.88		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		906090 PP1A_HUMAN (1-330): 0: 614: 100.00		LMTK3_HUMAN (7-1342): 9.67e-159: 518: 29.10
+	Hs
		384599 PP1A_HUMAN (1-330): 0: 614: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384600 PP1B_HUMAN (1-330): 0: 568: 87.88		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384627 PP2AA_HUMAN (8-302): 3.14e-176: 492: 47.30		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77