HitPredict

Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 26116754, 28330616
Identification Methods affinity chromatography technology, proximity labelling technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~PDZ, PDZ~STPPase_N
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0007049 - cell cycle
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 330
Hs

1 1356
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024