HitPredict

Interactor 1: PP1A (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: Ppp1ca

Interactor 2: PP1R7 (Q3UM45)
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene: Ppp1r7

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	29669786, 25593058
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_9~Metallophos, LRR_9~STPPase_N
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Mm			1 361
+	Hs
		905917 PP1A_HUMAN (1-330): 0: 614: 99.70		PP1R7_HUMAN (1-361): 2.85e-60: 199: 93.91
+	Hs
		737822 PP1G_HUMAN (1-330): 0: 579: 90.36		PP1R7_HUMAN (1-361): 2.85e-60: 199: 93.91
+	Hs
		906470 PP1B_HUMAN (1-330): 0: 568: 87.58		PP1R7_HUMAN (1-361): 2.85e-60: 199: 93.91
+	Hs
		906094 PP1A_HUMAN (1-330): 0: 614: 99.70		ERBIN_HUMAN (2-295): 9.65e-34: 134: 19.14
+	Hs
		905890 PP1A_HUMAN (1-330): 0: 614: 99.70		SCRIB_HUMAN (9-228): 3.78e-30: 123: 16.40
+	Sc
		696298 PP12_YEAST (3-307): 0: 551: 83.93		SDS22_YEAST (40-360): 5.06e-47: 164: 43.84
+	Hs
		905863 PP1A_HUMAN (1-330): 0: 614: 99.70		FLII_HUMAN (7-198): 1.89e-22: 101: 13.31
+	Hs
		737994 PP1G_HUMAN (1-330): 0: 579: 90.36		ERBIN_HUMAN (2-295): 9.65e-34: 134: 19.14
+	Hs
		737799 PP1G_HUMAN (1-330): 0: 579: 90.36		SCRIB_HUMAN (9-228): 3.78e-30: 123: 16.40
+	Dm
		524622 PP12_DROME (7-304): 0: 553: 92.95		SCRIB_DROME (10-257): 9.18e-38: 146: 16.73
+	Ca
		1124021 Q59N42_CANAL (3-330): 0: 561: 81.10		Q5AHH6_CANAL (45-264): 3e-36: 136: 29.46
+	Hs
		906454 PP1B_HUMAN (1-330): 0: 568: 87.58		SCRIB_HUMAN (9-228): 3.78e-30: 123: 16.40
+	Hs
		737779 PP1G_HUMAN (1-330): 0: 579: 90.36		FLII_HUMAN (7-198): 1.89e-22: 101: 13.31
+	Hs
		906437 PP1B_HUMAN (1-330): 0: 568: 87.58		FLII_HUMAN (7-198): 1.89e-22: 101: 13.31
+	Ce
		800282 GLC7A_CAEEL (1-320): 0: 555: 84.26		SDS22_CAEEL (8-243): 7.77e-28: 112: 23.85
+	Dm
		819228 PP11_DROME (4-330): 0: 573: 87.46		Q9VEK8_DROME (231-361): 7.27e-14: 73.3: 23.66
+	Sp
		605293 PP12_SCHPO (8-303): 0: 538: 79.39		SDS22_SCHPO (160-359): 4.9e-26: 108: 30.50
+	Dm
		524647 PP12_DROME (7-304): 0: 553: 92.95		Q9VEK8_DROME (231-361): 7.27e-14: 73.3: 23.66
+	Dm
		819306 PP1B_DROME (6-326): 0: 551: 83.18		Q9VEK8_DROME (231-361): 7.27e-14: 73.3: 23.66
+	Dm
		984195 PP13_DROME (5-304): 0: 550: 91.33		Q9VEK8_DROME (231-361): 7.27e-14: 73.3: 23.66