HitPredict

Interactor 1: PP1A (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: Ppp1ca

Interactor 2: ASPP1 (Q62415)
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Gene: Ppp1r13b

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25593058
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Mm			1 1087
+	Hs
		906081 PP1A_HUMAN (1-330): 0: 614: 99.70		ASPP1_HUMAN (1-1087): 1.95e-166: 521: 91.28
+	Hs
		905884 PP1A_HUMAN (1-330): 0: 614: 99.70		ASPP2_HUMAN (1-1087): 1.08e-159: 504: 45.55
+	Mm
		93784 PP1A_MOUSE (1-330): 0: 614: 100.00		E9QJU8_MOUSE (1-1087): 1.87e-153: 488: 44.83
+	Hs
		737795 PP1G_HUMAN (1-330): 0: 579: 90.36		ASPP2_HUMAN (1-1087): 1.08e-159: 504: 45.55
+	Hs
		905849 PP1A_HUMAN (1-330): 0: 614: 99.70		Q05BL1_HUMAN (93-1087): 2.77e-106: 359: 43.83
+	Hs
		737760 PP1G_HUMAN (1-330): 0: 579: 90.36		Q05BL1_HUMAN (93-1087): 2.77e-106: 359: 43.83
+	Mm
		906260 PP1A_MOUSE (1-330): 0: 614: 100.00		IASPP_MOUSE (294-1086): 5.98e-60: 223: 21.87
+	Hs
		906042 PP1A_HUMAN (1-330): 0: 614: 99.70		IASPP_HUMAN (355-1086): 1.53e-56: 213: 23.51
+	Hs
		225132 PP1A_HUMAN (1-330): 0: 614: 99.70		MYPT2_HUMAN (854-994): 1.75e-43: 173: 32.62
+	Hs
		225129 PP1G_HUMAN (1-330): 0: 579: 90.36		MYPT2_HUMAN (854-994): 1.75e-43: 173: 32.62
+	Hs
		906000 PP1A_HUMAN (1-330): 0: 614: 99.70		PPR27_HUMAN (879-995): 7.54e-28: 112: 30.51
+	Hs
		906079 PP1A_HUMAN (1-330): 0: 614: 99.70		PP16A_HUMAN (898-996): 4.03e-19: 94.2: 35.35
+	Hs
		906099 PP1A_HUMAN (1-330): 0: 614: 99.70		PP16B_HUMAN (904-996): 5.86e-18: 90.7: 38.71
+	Hs
		161347 PP1A_HUMAN (1-330): 0: 614: 99.70		MYPT1_HUMAN (918-1018): 3.6e-14: 79.6: 32.67
+	Mm
		906366 PP1A_MOUSE (1-330): 0: 614: 100.00		MYPT1_MOUSE (918-1018): 9.82e-14: 78: 32.67
+	Mm
		906293 PP1A_MOUSE (1-330): 0: 614: 100.00		MYPT2_MOUSE (918-994): 4.64e-10: 66.1: 32.47
+	Mm
		906252 PP1A_MOUSE (1-330): 0: 614: 100.00		PP12C_MOUSE (918-995): 6.17e-10: 65.7: 32.05
+	Hs
		906116 PP1A_HUMAN (1-330): 0: 614: 99.70		PP12C_HUMAN (918-993): 4.31e-09: 62.6: 31.58
+	Hs
		161322 PP1G_HUMAN (1-330): 0: 579: 90.36		MYPT1_HUMAN (918-1018): 3.6e-14: 79.6: 32.67
+	Mm
		926555 PP1G_MOUSE (1-330): 0: 579: 90.36		MYPT1_MOUSE (918-1018): 9.82e-14: 78: 32.67