HitPredict

Interactor 1: PP1A (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: Ppp1ca

Interactor 2: PP1RB (Q8K1L5)
E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Protein phosphatase 1 regulatory subunit 11) (T-complex testis expressed protein 5) (Tctex-5)
Gene: Ppp1r11

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29669786
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008157 - protein phosphatase 1 binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Mm			1 131
+	Hs
		246077 PP1A_HUMAN (1-330): 0: 614: 99.70		PP1RB_HUMAN (1-107): 1.1e-33: 115: 84.11
+	Mm
		60456 PP1A_MOUSE (1-330): 0: 614: 100.00		A5A4Y9_MOUSE (1-104): 7.13e-33: 113: 99.04
+	Dm
		819234 PP11_DROME (4-330): 0: 573: 87.46		Q9VRC5_DROME (2-108): 8.8e-36: 123: 32.71
+	Hs
		246074 PP1G_HUMAN (1-330): 0: 579: 90.36		PP1RB_HUMAN (1-107): 1.1e-33: 115: 84.11
+	Dm
		524654 PP12_DROME (7-304): 0: 553: 92.95		Q9VMI2_DROME (9-130): 4.95e-40: 133: 34.62
+	Hs
		246078 PP1B_HUMAN (1-330): 0: 568: 87.58		PP1RB_HUMAN (1-107): 1.1e-33: 115: 84.11
+	Dm
		524658 PP12_DROME (7-304): 0: 553: 92.95		Q9VRC5_DROME (2-108): 8.8e-36: 123: 32.71
+	Dm
		819322 PP1B_DROME (6-326): 0: 551: 83.18		Q9VRC5_DROME (2-108): 8.8e-36: 123: 32.71
+	Dm
		984199 PP13_DROME (5-304): 0: 550: 91.33		Q9VRC5_DROME (2-108): 8.8e-36: 123: 32.71
+	Sp
		145041 PP11_SCHPO (6-329): 0: 557: 82.10		YPI1_SCHPO (9-77): 6.15e-20: 80.3: 39.13
+	At
		819351 PP13_ARATH (4-326): 0: 548: 71.21		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		819352 PP14_ARATH (9-304): 0: 547: 78.72		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	Pf
		1212834 Q8ILV1_PLAF7 (6-304): 0: 551: 84.28		Q8IJ88_PLAF7 (19-76): 1.73e-18: 76.8: 44.83
+	At
		819359 PP16_ARATH (9-329): 0: 544: 73.21		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		819350 PP12_ARATH (2-302): 0: 540: 78.15		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		673655 PP11_ARATH (4-304): 0: 537: 76.90		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		819358 PP15_ARATH (2-306): 0: 525: 76.14		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		287759 PP17_ARATH (4-328): 0: 524: 72.00		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		1248172 PP19_ARATH (1-300): 0: 522: 73.36		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02
+	At
		287765 PP18_ARATH (5-300): 0: 521: 74.32		INH3_ARATH (10-103): 2.25e-20: 81.4: 34.02