HitPredict

Interactor 1: PP1A (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: Ppp1ca

Interactor 2: IPP2 (Q9DCL8)
Protein phosphatase inhibitor 2 (IPP-2)
Gene: Ppp1r2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	29669786, 25593058
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	GO:0005977 - glycogen metabolic process GO:0043197 - dendritic spine
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 330 Mm			1 206
+	Hs
		782714 PP1A_HUMAN (1-330): 0: 614: 99.70		IPP2_HUMAN (1-206): 2.54e-78: 234: 83.98
+	Hs
		905971 PP1A_HUMAN (1-330): 0: 614: 99.70		IPP2B_HUMAN (1-206): 2.14e-76: 230: 82.04
+	Hs
		164068 PP1A_HUMAN (1-330): 0: 614: 99.70		IPP2C_HUMAN (1-203): 6.65e-66: 203: 41.38
+	Hs
		737628 PP1G_HUMAN (1-330): 0: 579: 90.36		IPP2_HUMAN (1-206): 2.54e-78: 234: 83.98
+	Hs
		737869 PP1G_HUMAN (1-330): 0: 579: 90.36		IPP2B_HUMAN (1-206): 2.14e-76: 230: 82.04
+	Hs
		782715 PP1B_HUMAN (1-330): 0: 568: 87.58		IPP2_HUMAN (1-206): 2.54e-78: 234: 83.98
+	Hs
		906500 PP1B_HUMAN (1-330): 0: 568: 87.58		IPP2B_HUMAN (1-206): 2.14e-76: 230: 82.04
+	Hs
		164067 PP1G_HUMAN (1-330): 0: 579: 90.36		IPP2C_HUMAN (1-203): 6.65e-66: 203: 41.38
+	Hs
		164069 PP1B_HUMAN (1-330): 0: 568: 87.58		IPP2C_HUMAN (1-203): 6.65e-66: 203: 41.38
+	Dm
		65575 PP11_DROME (4-330): 0: 573: 87.46		A8JNP7_DROME (1-162): 1.5e-38: 136: 38.27
+	Ce
		821925 GLC7B_CAEEL (3-329): 0: 588: 90.21		Q9N537_CAEEL (46-156): 1.45e-28: 107: 42.62
+	Dm
		819222 PP11_DROME (4-330): 0: 573: 87.46		Q9V3C7_DROME (1-162): 2.24e-32: 117: 38.27
+	Dm
		65574 PP12_DROME (7-304): 0: 553: 92.95		A8JNP7_DROME (1-162): 1.5e-38: 136: 38.27
+	Dm
		65576 PP1B_DROME (6-326): 0: 551: 83.18		A8JNP7_DROME (1-162): 1.5e-38: 136: 38.27
+	Dm
		65577 PP13_DROME (5-304): 0: 550: 91.33		A8JNP7_DROME (1-162): 1.5e-38: 136: 38.27
+	Dm
		524639 PP12_DROME (7-304): 0: 553: 92.95		Q9V3C7_DROME (1-162): 2.24e-32: 117: 38.27
+	Dm
		819290 PP1B_DROME (6-326): 0: 551: 83.18		Q9V3C7_DROME (1-162): 2.24e-32: 117: 38.27
+	Dm
		984191 PP13_DROME (5-304): 0: 550: 91.33		Q9V3C7_DROME (1-162): 2.24e-32: 117: 38.27
+	Ce
		1099877 GLC7A_CAEEL (1-320): 0: 555: 84.26		Q9N537_CAEEL (46-156): 1.45e-28: 107: 42.62