HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Metallophos
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 377
+	Hs
		891663 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		906403 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		906406 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		905825 PP1A_HUMAN (1-326): 0: 576: 88.79		ACTS_HUMAN (1-377): 0: 605: 100.00
+	Hs
		891662 PP1A_HUMAN (1-326): 0: 576: 88.79		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Mm
		906230 PP1A_MOUSE (1-326): 0: 576: 88.49		ACTG_MOUSE (4-377): 0: 604: 93.85
+	Hs
		737677 PP1G_HUMAN (1-327): 0: 569: 86.89		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		737730 PP1G_HUMAN (1-327): 0: 569: 86.89		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		737734 PP1G_HUMAN (1-327): 0: 569: 86.89		ACTC_HUMAN (1-377): 0: 604: 98.94