HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: RRP1B (Q14684)
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)
Gene: RRP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	27173435, 35235311, 20926688
Identification Methods	affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 758
+	Hs
		905896 PP1A_HUMAN (1-326): 0: 576: 88.79		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Hs
		737802 PP1G_HUMAN (1-327): 0: 569: 86.89		RRP1B_HUMAN (1-758): 6.96e-155: 470: 100.00
+	Sc
		696293 PP12_YEAST (1-308): 0: 547: 81.49		RRP1_YEAST (12-258): 2.73e-71: 236: 27.93
+	Hs
		905838 PP1A_HUMAN (1-326): 0: 576: 88.79		ANK2_HUMAN (222-733): 8.46e-28: 123: 13.03
+	Dm
		113980 PP1B_DROME (1-322): 0: 568: 90.37		M9PB30_DROME (225-624): 2.25e-10: 66.8: 8.33