HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: PPR3A (Q16821)
Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1)
Gene: PPP1R3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	15016827, 24366813
Identification Methods	affinity chromatography technology, pull down, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005977 - glycogen metabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 1122
+	Hs
		905933 PP1A_HUMAN (1-326): 0: 576: 88.79		PPR3A_HUMAN (1-1122): 0: 1725: 100.00
+	Hs
		737831 PP1G_HUMAN (1-327): 0: 569: 86.89		PPR3A_HUMAN (1-1122): 0: 1725: 100.00
+	Mm
		906352 PP1A_MOUSE (1-326): 0: 576: 88.49		PPR3A_MOUSE (1-1122): 0: 1577: 61.31
+	Hs
		906639 PP1B_HUMAN (1-327): 0: 597: 100.00		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		906203 PP1A_HUMAN (1-326): 0: 576: 88.79		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		738131 PP1G_HUMAN (1-327): 0: 569: 86.89		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		906518 PP1B_HUMAN (1-327): 0: 597: 100.00		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Hs
		319093 PP1A_HUMAN (1-326): 0: 576: 88.79		PPR3D_HUMAN (38-234): 7.09e-77: 257: 27.40
+	Hs
		319090 PP1G_HUMAN (1-327): 0: 569: 86.89		PPR3D_HUMAN (38-234): 7.09e-77: 257: 27.40
+	Hs
		906001 PP1A_HUMAN (1-326): 0: 576: 88.79		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Hs
		737903 PP1G_HUMAN (1-327): 0: 569: 86.89		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Mm
		57204 PP1A_MOUSE (1-326): 0: 576: 88.49		A2AJW4_MOUSE (38-234): 5.12e-69: 234: 26.44
+	Dm
		819235 PP11_DROME (6-327): 0: 567: 85.09		Q9VUF3_DROME (39-283): 3.86e-65: 227: 24.13
+	Dm
		819280 PP1B_DROME (1-322): 0: 568: 90.37		Q8SWT8_DROME (39-283): 1.16e-65: 226: 24.13
+	Dm
		819218 PP11_DROME (6-327): 0: 567: 85.09		Q8SWT8_DROME (39-283): 1.16e-65: 226: 24.13
+	Ce
		109596 GLC7B_CAEEL (1-326): 0: 580: 86.02		H2KYT5_CAEEL (49-240): 1.4e-57: 205: 25.49
+	Ce
		821923 GLC7B_CAEEL (1-326): 0: 580: 86.02		Q400N3_CAEEL (49-240): 1.93e-57: 204: 25.49
+	Dm
		819327 PP1B_DROME (1-322): 0: 568: 90.37		GBS76_DROME (38-269): 3.35e-53: 200: 28.51
+	Hs
		81860 PP1A_HUMAN (1-326): 0: 576: 88.79		PP13G_HUMAN (45-229): 6.09e-52: 188: 26.14
+	Hs
		906138 PP1A_HUMAN (1-326): 0: 576: 88.79		PPR3E_HUMAN (41-247): 3.43e-52: 186: 24.32