HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: IPP2B (Q6NXS1)
Protein phosphatase inhibitor 2 family member B (PPP1R2 family member B) (Protein phosphatase 1, regulatory subunit 2 pseudogene 3) (Protein phosphatase inhibitor 2-like protein 3)
Gene: PPP1R2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	25416956, unassigned1304
Identification Methods	validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	GO:0005977 - glycogen metabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 205
+	Hs
		782715 PP1B_HUMAN (1-327): 0: 597: 100.00		IPP2_HUMAN (1-205): 4.81e-75: 226: 95.61
+	Hs
		782714 PP1A_HUMAN (1-326): 0: 576: 88.79		IPP2_HUMAN (1-205): 4.81e-75: 226: 95.61
+	Hs
		905971 PP1A_HUMAN (1-326): 0: 576: 88.79		IPP2B_HUMAN (1-205): 4.26e-75: 226: 100.00
+	Mm
		906370 PP1A_MOUSE (1-326): 0: 576: 88.49		IPP2_MOUSE (1-205): 1.16e-72: 220: 82.04
+	Hs
		737628 PP1G_HUMAN (1-327): 0: 569: 86.89		IPP2_HUMAN (1-205): 4.81e-75: 226: 95.61
+	Hs
		737869 PP1G_HUMAN (1-327): 0: 569: 86.89		IPP2B_HUMAN (1-205): 4.26e-75: 226: 100.00
+	Hs
		164069 PP1B_HUMAN (1-327): 0: 597: 100.00		IPP2C_HUMAN (1-198): 1.84e-56: 179: 43.22
+	Hs
		164068 PP1A_HUMAN (1-326): 0: 576: 88.79		IPP2C_HUMAN (1-198): 1.84e-56: 179: 43.22
+	Hs
		164067 PP1G_HUMAN (1-327): 0: 569: 86.89		IPP2C_HUMAN (1-198): 1.84e-56: 179: 43.22
+	Dm
		65576 PP1B_DROME (1-322): 0: 568: 90.37		A8JNP7_DROME (1-161): 2.83e-49: 164: 38.51
+	Dm
		65575 PP11_DROME (6-327): 0: 567: 85.09		A8JNP7_DROME (1-161): 2.83e-49: 164: 38.51
+	Ce
		821925 GLC7B_CAEEL (1-326): 0: 580: 86.02		Q9N537_CAEEL (1-155): 2.44e-38: 132: 33.72
+	Dm
		65574 PP12_DROME (6-303): 0: 546: 88.59		A8JNP7_DROME (1-161): 2.83e-49: 164: 38.51
+	Dm
		819260 PP1B_DROME (1-322): 0: 568: 90.37		Q4V424_DROME (40-198): 2.22e-39: 138: 20.36
+	Dm
		819290 PP1B_DROME (1-322): 0: 568: 90.37		Q9V3C7_DROME (1-161): 1.01e-40: 138: 38.51
+	Dm
		819222 PP11_DROME (6-327): 0: 567: 85.09		Q9V3C7_DROME (1-161): 1.01e-40: 138: 38.51
+	Ce
		1099877 GLC7A_CAEEL (3-317): 0: 569: 92.38		Q9N537_CAEEL (1-155): 2.44e-38: 132: 33.72
+	Dm
		1118462 Q8T0U6_DROME (18-322): 0: 550: 91.48		Q4V424_DROME (40-198): 2.22e-39: 138: 20.36
+	Dm
		524615 PP12_DROME (6-303): 0: 546: 88.59		Q4V424_DROME (40-198): 2.22e-39: 138: 20.36
+	Dm
		524639 PP12_DROME (6-303): 0: 546: 88.59		Q9V3C7_DROME (1-161): 1.01e-40: 138: 38.51