HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: SFRP1 (Q8N474)
Secreted frizzled-related protein 1 (FRP-1) (sFRP-1) (Secreted apoptosis-related protein 2) (SARP-2)
Gene: SFRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17123353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 314
+	Hs
		906019 PP1A_HUMAN (1-326): 0: 576: 88.79		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		737920 PP1G_HUMAN (1-327): 0: 569: 86.89		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		906488 PP1B_HUMAN (1-327): 0: 597: 100.00		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		905956 PP1A_HUMAN (1-326): 0: 576: 88.79		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		737855 PP1G_HUMAN (1-327): 0: 569: 86.89		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		906559 PP1B_HUMAN (1-327): 0: 597: 100.00		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		906078 PP1A_HUMAN (1-326): 0: 576: 88.79		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		737974 PP1G_HUMAN (1-327): 0: 569: 86.89		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59