HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, PDZ~STPPase_N
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 541
+	Rn
		193533 PP1B_RAT (1-327): 0: 597: 100.00		NEB1_RAT (40-375): 5.28e-41: 160: 14.43
+	Hs
		906629 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		906570 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Rn
		192520 PP1B_RAT (1-327): 0: 597: 100.00		NEB2_RAT (40-314): 1.07e-33: 138: 17.98
+	Mm
		906654 PP1B_MOUSE (1-327): 0: 597: 100.00		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		906197 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Rn
		193534 PP1G_RAT (1-327): 0: 569: 86.89		NEB1_RAT (40-375): 5.28e-41: 160: 14.43
+	Hs
		738120 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		906098 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Rn
		192519 PP1A_RAT (1-326): 0: 576: 88.79		NEB2_RAT (40-314): 1.07e-33: 138: 17.98
+	Mm
		906288 PP1A_MOUSE (1-326): 0: 576: 88.49		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		737997 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Rn
		192521 PP1G_RAT (1-327): 0: 569: 86.89		NEB2_RAT (40-314): 1.07e-33: 138: 17.98
+	Mm
		926545 PP1G_MOUSE (1-327): 0: 569: 86.89		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		906269 PP1A_MOUSE (1-326): 0: 576: 88.49		SNTA1_MOUSE (4-188): 3.93e-30: 125: 18.75
+	Hs
		738074 PP1G_HUMAN (1-327): 0: 569: 86.89		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		738019 PP1G_HUMAN (1-327): 0: 569: 86.89		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Mm
		926540 PP1G_MOUSE (1-327): 0: 569: 86.89		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		102367 PP1B_HUMAN (1-327): 0: 597: 100.00		G3V1L9_HUMAN (4-254): 6.04e-12: 70.7: 13.97
+	Hs
		906425 PP1B_HUMAN (1-327): 0: 597: 100.00		ZO1_HUMAN (4-254): 7.48e-12: 70.3: 13.97