HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	26496610, 27880917, 28330616
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0007049 - cell cycle GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 2365
+	Hs
		906127 PP1A_HUMAN (1-326): 0: 576: 88.79		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		738038 PP1G_HUMAN (1-327): 0: 569: 86.89		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		906507 PP1B_HUMAN (1-327): 0: 597: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		737880 PP1G_HUMAN (1-327): 0: 569: 86.89		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Dm
		819289 PP1B_DROME (1-322): 0: 568: 90.37		MYSN_DROME (1678-2364): 1.82e-45: 184: 12.70
+	Hs
		528366 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH6_HUMAN (1655-2365): 7.59e-43: 175: 10.13
+	Mm
		906349 PP1A_MOUSE (1-326): 0: 576: 88.49		TARA_MOUSE (31-1991): 1.44e-42: 174: 14.58
+	Mm
		906240 PP1A_MOUSE (1-326): 0: 576: 88.49		MYH6_MOUSE (1655-2365): 4.1e-42: 173: 9.99
+	Hs
		724747 PP1B_HUMAN (1-327): 0: 597: 100.00		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		724746 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		724689 PP1G_HUMAN (1-327): 0: 569: 86.89		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Dm
		113980 PP1B_DROME (1-322): 0: 568: 90.37		M9PB30_DROME (2-562): 8.22e-28: 126: 7.81
+	Dm
		404229 PP1B_DROME (1-322): 0: 568: 90.37		MYSA_DROME (1845-2365): 4.35e-27: 123: 10.60
+	Hs
		906466 PP1B_HUMAN (1-327): 0: 597: 100.00		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Dm
		404244 Q8T0U6_DROME (18-322): 0: 550: 91.48		MYSA_DROME (1845-2365): 4.35e-27: 123: 10.60
+	Hs
		108761 PP1B_HUMAN (1-327): 0: 597: 100.00		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Hs
		905894 PP1A_HUMAN (1-326): 0: 576: 88.79		MDC1_HUMAN (88-903): 1.81e-15: 85.4: 14.49
+	Hs
		737818 PP1G_HUMAN (1-327): 0: 569: 86.89		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		905838 PP1A_HUMAN (1-326): 0: 576: 88.79		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		725131 PP2AB_HUMAN (8-303): 1.26e-176: 492: 46.13		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89