HitPredict

Interactor 1: PRS4 (P62191)
26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: PSMC1

Interactor 2: UBCP1 (Q8WVY7)
Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)
Gene: UBLCP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.825

Property	Details
Experiments	27880917, 28539385
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 318
+	Hs
		913325 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		UBCP1_HUMAN (1-318): 1.78e-170: 477: 100.00
+	Hs
		907108 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		UBCP1_HUMAN (1-318): 1.78e-170: 477: 100.00
+	Hs
		798723 PRS6B_HUMAN (50-433): 1.06e-122: 364: 48.96		UBCP1_HUMAN (1-318): 1.78e-170: 477: 100.00
+	Hs
		870728 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		UBP14_HUMAN (2-109): 1.8e-29: 119: 29.63
+	Hs
		870733 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		UBP14_HUMAN (2-109): 1.8e-29: 119: 29.63
+	Hs
		870729 PRS8_HUMAN (55-433): 1.06e-123: 366: 46.70		UBP14_HUMAN (2-109): 1.8e-29: 119: 29.63
+	Hs
		798619 PRS6B_HUMAN (50-433): 1.06e-122: 364: 48.96		UBP14_HUMAN (2-109): 1.8e-29: 119: 29.63
+	Sp
		736969 PRS4_SCHPO (7-435): 5.88e-125: 371: 72.85		UBP6_SCHPO (1-88): 8.88e-24: 102: 38.64
+	Sp
		252275 PRS6B_SCHPO (65-422): 1.07e-117: 350: 49.58		UBP6_SCHPO (1-88): 8.88e-24: 102: 38.64