HitPredict

Interactor 1: PRS4 (P62193)
26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: Psmc1

Interactor 2: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20178748
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 440 Rn			1 415
+	Hs
		872248 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51
+	Rn
		1104198 Q32PW9_RAT (66-438): 1.52e-126: 373: 40.75		RD23B_RAT (1-415): 3.84e-120: 357: 100.00
+	Hs
		872250 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51
+	Hs
		872133 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46
+	Hs
		906946 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60
+	Sc
		697092 PRS4_YEAST (1-440): 2.21e-129: 382: 71.36		RAD23_YEAST (1-413): 1.14e-72: 234: 26.82
+	At
		1352317 PRS4A_ARATH (1-440): 1.58e-135: 398: 76.30		DSK2A_ARATH (1-413): 7.19e-64: 215: 14.88
+	Dm
		820528 PRS4_DROME (1-440): 1.71e-137: 403: 91.36		Q9VWD9_DROME (1-363): 1.21e-59: 204: 13.70
+	Dm
		186163 PRS8_DROME (57-433): 1.81e-127: 376: 46.95		Q9VWD9_DROME (1-363): 1.21e-59: 204: 13.70
+	Hs
		906941 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Hs
		906929 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		UBQL4_HUMAN (1-363): 9.84e-41: 154: 14.29
+	Dm
		186166 PRS8_DROME (57-433): 1.81e-127: 376: 46.95		Q9VXF9_DROME (1-412): 2.46e-53: 185: 13.94
+	Hs
		906808 PRS4_HUMAN (1-440): 8.84e-140: 409: 100.00		RL40_HUMAN (1-112): 6.75e-40: 140: 24.11
+	Hs
		913364 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22
+	Mm
		476744 PRS4_MOUSE (1-440): 8.84e-140: 409: 100.00		UBC_MOUSE (1-110): 8.25e-31: 126: 23.64
+	Hs
		913358 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		UBQL4_HUMAN (1-363): 9.84e-41: 154: 14.29
+	Hs
		913240 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		RL40_HUMAN (1-112): 6.75e-40: 140: 24.11
+	Mm
		476747 PRS10_MOUSE (66-438): 7.99e-126: 371: 40.75		UBC_MOUSE (1-110): 8.25e-31: 126: 23.64
+	Dm
		820508 PRS4_DROME (1-440): 1.71e-137: 403: 91.36		Q9VCD5_DROME (1-207): 8.28e-16: 79.1: 16.67
+	Hs
		913239 PRS10_HUMAN (66-438): 7.99e-126: 371: 40.75		RS27A_HUMAN (1-91): 4.3e-16: 76.9: 26.37