HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 128
+	At
		1092354 PRS4B_ARATH (19-396): 1.44e-158: 455: 47.62		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1092413 PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		906808 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		906982 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	At
		1092308 PRS6B_ARATH (2-403): 2.14e-137: 400: 40.05		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		474950 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	At
		1092307 PS10A_ARATH (16-403): 1.49e-121: 359: 43.22		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		730236 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	At
		1092378 PRS7A_ARATH (81-392): 1.93e-115: 345: 56.09		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1092219 CD48E_ARATH (135-382): 2.65e-82: 270: 40.32		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1092294 CD48D_ARATH (135-382): 5.13e-82: 269: 39.11		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		913240 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		913239 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	At
		1092257 PS10B_ARATH (8-125): 2.97e-11: 66.7: 6.78		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091926 PRS8B_ARATH (9-123): 1.82e-10: 64.4: 6.96		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091962 PRS8A_ARATH (9-123): 1.96e-10: 64: 6.96		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59