HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: HNF4G (Q14541)
Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2)
Gene: HNF4G

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 408
+	Hs
		587150 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RXRA_HUMAN (5-332): 5.69e-118: 353: 40.90
+	Hs
		500362 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARB_HUMAN (10-373): 2.2e-110: 333: 26.26
+	Hs
		906980 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ERR3_HUMAN (5-327): 2.77e-104: 317: 27.08
+	Hs
		369311 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ESR1_HUMAN (1-367): 1.12e-99: 310: 24.40
+	Hs
		530791 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARG_HUMAN (10-361): 2.65e-101: 310: 26.03
+	Hs
		907111 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ESR2_HUMAN (10-325): 6.12e-99: 306: 28.57
+	Hs
		487934 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		RARA_HUMAN (10-333): 1.73e-99: 305: 27.00
+	Hs
		611412 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		NR4A1_HUMAN (7-331): 1.24e-95: 300: 26.55
+	Hs
		369310 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		ESR1_HUMAN (1-367): 1.12e-99: 310: 24.40
+	Rn
		411261 PRS8_RAT (1-406): 1.42e-136: 398: 100.00		ESR1_RAT (1-368): 6.07e-93: 293: 25.06
+	Hs
		906889 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		ESR2_HUMAN (10-325): 6.12e-99: 306: 28.57
+	Hs
		510012 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		ERR1_HUMAN (5-327): 1.58e-92: 286: 27.22
+	Hs
		611411 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		NR4A1_HUMAN (7-331): 1.24e-95: 300: 26.55
+	Hs
		369145 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		ESR1_HUMAN (1-367): 1.12e-99: 310: 24.40
+	Hs
		798727 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		ESR2_HUMAN (10-325): 6.12e-99: 306: 28.57
+	Hs
		369100 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		ESR1_HUMAN (1-367): 1.12e-99: 310: 24.40
+	Hs
		730322 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		ESR2_HUMAN (10-325): 6.12e-99: 306: 28.57
+	Hs
		369327 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		ESR1_HUMAN (1-367): 1.12e-99: 310: 24.40
+	Hs
		913328 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		ESR2_HUMAN (10-325): 6.12e-99: 306: 28.57