HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: CC74B (Q96LY2)
Coiled-coil domain-containing protein 74B
Gene: CCDC74B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 380
+	Hs
		907121 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		CC74A_HUMAN (1-380): 0: 673: 97.63
+	Hs
		906903 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		CC74B_HUMAN (1-380): 0: 681: 100.00
+	Hs
		906894 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		CC74A_HUMAN (1-380): 0: 673: 97.63
+	Hs
		798736 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		CC74B_HUMAN (1-380): 0: 681: 100.00
+	Hs
		798729 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		CC74A_HUMAN (1-380): 0: 673: 97.63
+	Hs
		730335 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		CC74B_HUMAN (1-380): 0: 681: 100.00
+	Hs
		730325 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		CC74A_HUMAN (1-380): 0: 673: 97.63
+	Hs
		913335 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		CC74B_HUMAN (1-380): 0: 681: 100.00
+	Hs
		913332 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		CC74A_HUMAN (1-380): 0: 673: 97.63